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Serotonin levels in synapses are reduced by two kinds of presynaptic molecules: autoreceptors (orange), which direct the cells to inhibit serotonin production, and reuptake transporters (yellow), which absorb the neurotransmitter. Several antidepressants, including Prozac and Paxil, increase synaptic serotonin by inhibiting its reuptake. nephrine reuptake, and so increase norepinephrine in synapses, are effective antidepressants in many people. S. and is awaiting approval here. Serotonin Connections T he data connecting norepinephrine to depression are solid and still growing.

Harris Professor and chairman of the department of psychiatry and behavioral sciences at the Emory University School of Medicine. D. D. (in neurobiology) from the University of North Carolina at Chapel Hill and received psychiatry training there and at Duke University, where he joined the faculty. In 1991 he moved to Emory. Nemeroff has won several awards for his research in biological psychiatry and is immediate past president of the American College of Neuropsychopharmacology. Biology of Depressive Disorders, Parts A and B.

Some reputable as- 200 100 0 0 2 4 6 8 10 12 14 COSMIC TIME (BILLIONS OF YEARS) the quasar astronomer. First, how are quasars related to galaxies and stars? Second, how long does each quasar pour out its enormous energy? In our immediate cosmic neighborhood—within one billion light-years from the earth—there is only one quasar for every million galaxies. But that does not necessarily mean that quasars are much rarer than galaxies; they could be just as common but have much shorter luminous lifetimes.

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