Download Defects of Secretion in Cystic Fibrosis by Marsh M. Reddy, Andres Ponce, Paul M. Quinton (auth.), PDF

By Marsh M. Reddy, Andres Ponce, Paul M. Quinton (auth.), Carsten Schultz (eds.)

Defects in Secretion of Cystic Fibrosis offers an outline on present examine from prime specialists in North the US and Europe. This replace on cystic fibrosis presents extensive unique paintings in addition to evaluate fabric on the various correct physiological and molecular subject matters within the box. matters lined comprise the interaction of many of the epithelial ion channels, the underlying intracellular sign transduction, mucus secretion, and novel ways to advance medicines opposed to cystic fibrosis. This publication brings jointly physicians, physiologists, and different scientists serious about simple study, from molecular biology to drug layout and introduces novel investigative and healing elements of secretion problems suitable in cystic fibrosis and similar diseases.

This ebook could be of curiosity to Molecular biologists, physiologists, scientists operating in pharmaceutical learn and drug developement, physicians and researchers in Cystic fibrosis and similar diseases.

Show description

Read Online or Download Defects of Secretion in Cystic Fibrosis PDF

Similar nonfiction_9 books

Transplantation Pathology: A Guide for Practicing Pathologists

Basic pathologists see many biopsies from transplanted organs yet few are in big enough centres in order that this types the majority in their paintings. The e-book describes the adjustments which might be saw in transplantation in all the significant organ structures which are sometimes transplanted and there are bills of the pathology of infections and of the immunological problems which are confronted via those sufferers.

Coupling of Biological and Electronic Systems: Proceedings of the 2nd caesarium, Bonn, November 1–3, 2000

The coupling of organic and digital structures has some time past few years emerged as a box of accelerating value. Achievements just like the cardiac pacemaker have prepared the ground for extra subtle ways, equivalent to the lab-on-a-chip and DNA pcs. This publication offers experiences on the most promising initiatives during this interdisciplinary learn box, overlaying issues from bioinformatics to biosensor expertise.

Biology of the Antarctic Seas XI

In regards to the ProductPublished by way of the yankee Geophysical Union as a part of the Antarctic examine sequence. content material:

Drops and Bubbles in Contact with Solid Surfaces

The 3rd quantity in a sequence devoted to colloids and interfaces, Drops and Bubbles involved with reliable Surfaces offers an up to date assessment of the basics and functions of drops and bubbles and their interplay with stable surfaces. The chapters hide the theoretical and experimental facets of wetting and wettability, liquid–solid interfacial homes, and spreading dynamics on various surfaces, together with a different part on polymers.

Additional resources for Defects of Secretion in Cystic Fibrosis

Sample text

Rapid regulation of electrolyte absorption in sweat duct. J. Membr. Biol 140, 57-67 (1994). 25. M. M. Reddy and P. M. Quinton. Deactivation of CFTR-Cl conductance by endogenous phosphatases in the native sweat duct. Am. J. Physiol 270, C474-80 (1996). 26. D. N. Sheppard, et al. Mutations in CFTR associated with mild-disease-form CI- channels with altered pore properties. Nature 362, 160-4 (1993). 27. J. Y. Choi, et al. Aberrant CFTR-dependent HCOs" transport in mutations associated with cystic fibrosis.

117, 423-430 (2001). 17. J. H. Widdicombe, Regulation of the depth and composition of airway surface liquid, J. Anar. 201,313-318(2002). 18. P. M. Quinton, The neglected ion: HCO3", Nat. Med. 7, 292-293 (2001). 19. M. Mall, T. Gonska, J. Thomas, R. Schreiber, H. H. Seydewitz, J. Kuehr, M. Brandis and K. Kunzelmann, Role of basolateral K"^ channels in Ca^"^ activated CI' secretion in human normal and cystic fibrosis airway epithelia. Pediatric Research 53, 608-618 (2003). 20. M. Mall, A. Wissner, R.

Garty and L. G. Palmer, Epithelial sodium channels, Function, structure and regulation, Physiol. Rev. 11, 359-396 (1997). 107. R. Knowles, K. N. Olivier, K. W. Hohneker, J. Robinson, W. D. Bennett and R. C. Boucher, Pharmacologic treatment of abnormal ion transport in the airway epithelium in cystic fibrosis. Chest 107, 71S-76S (1995). 108. R. P. Tomkiewicz, E. M. App, J. G. Zayas, O. Ramirez, N. Church, R. C. Boucher, M. R. Knowles and M. King, Amiloride inhalation therapy in cystic fibrosis. Influence on ion content, hydration, and rheology of sputum.

Download PDF sample

Rated 4.98 of 5 – based on 8 votes