Download Coupling of Biological and Electronic Systems: Proceedings by Ch. Baumstark-Khan, Ch. E. Hellweg (auth.), Professor PDF

By Ch. Baumstark-Khan, Ch. E. Hellweg (auth.), Professor Karl-Heinz Hoffmann (eds.)

The coupling of organic and digital platforms has long ago few years emerged as a box of accelerating significance. Achievements just like the cardiac pacemaker have cleared the path for extra refined methods, comparable to the lab-on-a-chip and DNA pcs. This e-book provides experiences on essentially the most promising initiatives during this interdisciplinary examine box, overlaying themes from bioinformatics to biosensor expertise.

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5. , D. T . C. West cot t , Recon stitution of excit abl e membrane st ruc t ur e in vit ro. Cir culation 26:1167-1171 (1962). 6. , A. Darszon , and H. Schindler , Form ation of bimol ecular membranes from lipid monolayer s and a st udy of t heir elect rical propertie s. Proc. Na t l. Aca d . Sci. A. 69:3561-3566 (1972) . 7. , Ion Channel Recon stitution . Plenum P ress, New York (1987) . 8. P. , A. Marty, E . Neher , B. J. Sigwor th, Improved pat ch-cl amp t echniques for high-resolu tion cur rent recording from cells and cell-free membrane pat ches.

A way out of t his problem is the implementation of the reaction-diffusion kinetics dir ectly in configurable, par allel hardware . In contrast to convent iona l programming, dat a processing has to be organiz ed on t he level of logical primitiv es such as coun t ers, mul tiplexers and flip-flops. Reactions between two molecules represented by bit sequences are ty pically treat ed in a systolic manner (see Box 2) . In t he case of a par allel machine such as NG EN , the det ailed st ruct ure of the connect ion topology of t he indi vidually configure d processors must be org aniz ed tran sparently across FPGA chip and board boundaries.

I u 0 11 10 ~ ) 10 , I: • II U IS F ig. 7. Schematic descrip tion of t he fun ctionali ty of t he two dimen sional MargoIus algorit hm . The time development on the left hand side is from the upper left to the lower right . Taken a 16 elements clu ster for example the figure shows the clu stering of the plan e, t he indep enden t ro tation of every 2 x 2 clu st er , t he al ternat ing clu stering and again the rotation of the new clu sters. This procedures is repeated whi ch est abli she s un correlated diffu sion .

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