By Gary M. Baxter
The 6th version of Adams and Stashak’s Lameness in Horses builds at the book’s recognition because the vintage gold-standard reference on equine lameness. Now in complete colour, the textual content has been totally revised and streamlined to enhance user-friendliness, with a brand new, simplified layout and an improved emphasis at the analysis and administration of lameness. A beneficial supplementary DVD offers a whole advisor to diagnosing lameness, delivering extra anatomical pictures; movies demonstrating key systems corresponding to actual exam, flexion assessments, perineural and intrasynovial anesthesia; and examples of lameness stipulations in movement.
The 6th version offers new or considerably rewritten chapters at the axial skeleton, ideas of musculoskeletal illness, rules of treatment for lameness, occupation-related lameness stipulations, and lameness within the younger horse. The diagnostic approaches bankruptcy has additionally been considerably multiplied to mirror advances during this very important region. Adams and Stashak’s Lameness in Horses, 6th variation is an important addition to any equine practitioner’s bookshelf.
"This first-class textual content has built good from the former variants. it really is, I recommend, absolutely nonetheless an important addition to the bookcase of any perform that does an important volume of equine work." (Veterinary perform, 1 November 2011)
"The 6th version of this vintage will end up to be a very good source for equine practitioners, veterinary professional trainees, and scholars . . . Dr. Baxter and his colleagues are to be congratulated in this awesome book." (Doody's, 15 July 2011)
"The comprehensiveness of this paintings is nothing short of extra special. it really is centred, greatly illustrated and may definitely don't have any challengers to the identify because the bible on equine lameness . . . Adams and Stashak have a lot to be pleased with during this e-book, as does editor Baxter for his large enter. " (Horsetalk , 23 June 2011)
"The comprehensiveness of this paintings is nothing short of out of the ordinary. it truly is concentrated, broadly illustrated and may absolutely haven't any challengers to the name because the bible on equine lameness." (Horsetalk, June 2011)
"This publication continues to be a key textual content for equine clinicians, with specific strengths being the descriptive anatomy, summaries of diagnostic imaging concepts and the readability of the diagnostic ideas provided, either within the textual content and at the DVD." (Equine Veterinary schooling, could 2011)
"The most modern model of this vintage not just has up-to-date content material, yet comprises many color pictures and illustrations in addition to an accompanying DVD. The latter is a superb 'how to...' advisor to equine lameness research, with first-class sections on perineural and intrasynovial injection recommendations, which, in my view, is worthy part the acquisition rate all through itself... this ebook is still an asset to all people with an curiosity in equine lameness." (Veterinary list, April 2011)
From the again Cover
The 6th variation of Adams and Stashak’s Lameness in Horses builds at the book’s popularity because the vintage gold-standard reference on equine lameness. Now in complete colour, the textual content has been totally revised and streamlined to enhance user-friendliness, with a brand new, simplified structure and an improved emphasis at the analysis and administration of lameness. A important supplementary DVD presents a whole advisor to lameness prognosis, providing extra anatomical pictures; movies demonstrating key techniques akin to actual exam, flexion checks, perineural and intrasynovial anesthesia; and examples of lameness stipulations in movement.
The 6th version provides new or considerably rewritten chapters at the axial skeleton, rules of musculoskeletal sickness, ideas of remedy for lameness, occupation-related lameness stipulations, and lameness within the younger horse. The diagnostic tactics bankruptcy has additionally been considerably improved to mirror advances during this vital sector. Adams and Stashak’s Lameness in Horses, 6th variation, is an important addition to any equine practitioner’s bookshelf.
* totally revised re-creation of the vintage textual content on equine lameness
* provided with a simplified layout and diminished repetition to enhance ease of use
* targeted extra strongly on lameness and diagnostics
* bargains six new or considerably made over chapters and an multiplied diagnostic systems chapter
* features a DVD with useful vitamins, together with extra anatomical photos, movies demonstrating key strategies akin to intrasynovial injections, and examples of stipulations in motion
* Now in complete colour, with an enticing two-color textual content design
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Additional info for Adams and Stashak's Lameness in Horses (6th Edition)
Subsequent steps then allow metastatic cancer cells to enter and survive in the circulation. Cells then arrest at distant locations, extravasate, and survive in the microenvironment of the distant locations. Arrest of cells may be at the eventual secondary organ where metastasis becomes clinically evident or cells may initially arrest at a “sanctuary site” where they may lie dormant before moving on to the eventual secondary site. The cellular programs that result in a break of dormancy are not well understood.
43 Cancer cells can undergo a “metabolic switch” so that glucose is metabolized to lactate, in the presence or absence of oxygen, causing a net energy deficit. , GLUT-1), which increases uptake of glucose into the cytoplasm. This process is exploited in positron-emission tomography (PET) imaging as tumors will preferentially uptake a radiolabeled analog of glucose (18F-fluorodeoxyglucose [FDG]). 54 It is difficult to appreciate the survival advantage of this mechanism. One hypothesis is that the switch allows the diversion of glycolytic intermediates into other biosynthetic pathways that support the production of new cells.
In contrast, telomerase Chapter 2 Tumor Biology and Metastasis 39 Reprogramming Energy Metabolism Telomere lengths (Kbp) End replication problem Critically short length Senescence (M1) Crisis (M2) Population doublings • Figure 2-5 Telomeric attrition in cultured cells. In mammalian cells the DNA is organized into chromosomes within the nucleus, and these are capped by specialized DNA-protein structures known as telomeres. The major function of these structures is protection, but they are progressively eroded at each cell division because of the inability of DNA to completely replicate itself.